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us more tools designed for obese

PRINCESS! vz other science becomes an ally of ours, without even knowing it, thinking about overweight people have created a new medication to suppress appetite, which according to this article suggests is more powerful than the already well-known x
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Leptin, a hormone that suppresses hunger in people with good health, could be equally effective among the obese, which are resistant to its effects, thanks to drugs already on the market, according to a study on mice reported in the United States.
WASHINGTON (AFP)

Leptin, a hormone that suppresses hunger in healthy people, could become equally effective among the obese, which are resistant to its effects, thanks to drugs already on the market, according to a study on mice reported in the United States.
The discovery 10 years ago this hormone that regulates fat stores in the body had generated much hope in the fight against obesity.
But the euphoria quickly stopped when researchers found that leptin was ineffective in obese people because they are resistant to its effects.

"Most obese humans are resistant to leptin and the brain blocks their effects," said Umut Ozcan, the Faculty of Medicine, Harvard University, one of the authors of this study published in the journal Cell Metabolism January 7.

pharmaceutical firms and academic laboratories sought unsuccessfully du For years, a drug able to get the brain of obese leptin-sensitive back, "continued the doctor.

When his team tried Ozcan and obese mice with a fat-rich diet with one or another drug called Buphenyl (4-PBA) and tauroursodeoxycholic acid (TUDCA), the sensitivity of these animals to the effects of leptin was multiplied by 10.
All mice lost weight then, although still being fed high-fat meal, said the researchers.

"Our study is the first to show that it is possible to raise awareness for leptin to obese mice subjected to a high fat diet," said Ozcan.
"If this works in humans, it may be to obesity," he added.